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In the following list, we have evaluated every medication approved by the Food and Drug Administration (FDA) for the treatment of HIV. Our ratings are unscientific and subjective. They are based on the general feelings of people in the HIV community toward the pills they have to take. In each category, we’ve listed the preferred drugs first, and the less attractive alternatives later.

We strongly recommend that you discuss your medicines - and every other aspect of your treatment program - with a doctor who has extensive experience treating HIV and AIDS! However, if you’d like a general idea of how many pills you’re going to have to take, how they’re likely to affect your lifestyle, and what other people think about them, this review is for you.

Please note: although the medications in this review are listed individually, none of them (except Atripla, which is a combination of three drugs) is meant to be taken alone! Effective HIV therapy requires a medical regimen of at least three drugs.